Patientenkolloquium 2018
Das Universitätsklinikum Bonn möchte Sie auch 2018 wieder für das Patientenkolloquium "Uni-Medizin für Sie: Mitten im Leben" herzlich einladen ... weiterlesen

Research

Topics

   
Autoimmune disease

Our research focuses on the mechanisms by which cytoplasmic RNA sensors RIG-I like receptors (RLRs) distinguish between viral RNAs and self-RNAs and trigger type I IFNs. Current work examines spontaneous autoimmune symptoms in.RLR mutant mice derived via mutagenesis and how RLR-dysregulation causes autoimmune disease.

 
Viral recognition We are also particularly.interested in the analysis of immune responses and pathogenesis in virus infection in vivo and autoimmune diseases using.mouse models.